Does Modafinil Treat Obstructive Sleep Apnea?

Does Modafinil Treat Obstructive Sleep Apnea?

Modafinil is licensed for the treatment of narcolepsy, obstructive sleep apnea or hypopnea syndrome (added to continuous positive airway pressure), and chronic shift works sleep disorder when non-medicine approaches have not been effective.

Patients with mild to moderate OSA commonly suffer excessive daytime sleepiness and it is unclear whether modafinil treats this. In this study, we randomized untreated patients with mild to moderate OSA and significant daytime sleepiness to modafinil or placebo.


Modafinil is used to treat narcolepsy and obstructive sleep apnea or hypopnea syndrome (a breathing disorder that happens while you are sleeping). It is also use to help people with shift work sleep disorder. It is usually taken once a day in the morning with or without food.

The dosage of modafinil is based on your medical condition and response to treatment. It is important to take it exactly as your doctor has prescribed.

In a study of untreated patients with mild to moderate OSA, Modalert Australia significantly improved subjective daytime sleepiness and driving simulator performance. This effect was similar to the symptomatic benefit seen in CPAP-treated patients.

However, it is unclear whether modafinil can be use routinely in patients with mild to moderate OSA. Therefore, larger and longer confirmatory trials are need.

Side effects

Modafinil is an oral medicine that is licensed to treat residual sleepiness in patients with obstructive sleep apnea (OSA). Modalert and Waklert also work well as a wake-promoting agents to increase alertness.

However, this medication may cause side effects such as drowsiness, dizziness, trouble thinking or controlling movements, or difficulty seeing clearly. These effects can be serious and may be life-threatening if you take too much of this medicine.

This medicine is use to treat obstructive sleep apnea and narcolepsy. It also is use to help people who have shift work sleep disorder.

The most common side effects of modafinil include back pain, headache, nervousness, nausea, and stomach pain. If you experience any of these side effects, contact your doctor right away.

A small study found that modafinil was safe and effective in treating sleepiness in patients with mild to moderate OSA who were regular users of CPAP therapy. The results showed that the mean changes in ESS scores were significantly different between patients receiving nCPAP plus modafinil and placebo at weeks 1 and 4.


Using Modafinil for the treatment of obstructive sleep apnea may lead to serious side effects. Some people experience dizziness, drowsiness, trouble thinking, or trouble controlling their movements when they take this medicine.

Before you start using this medication, tell your doctor if you have any medical conditions or allergies. Also, tell your doctor if you are pregnant or breastfeeding.

Do not use this medication if you are allergic to it or to other wake-promoting medicines, such as ephedrine. It may also interact with other medications or supplements you are taking.

You should only take this medicine as directed by your doctor. Do not stop taking it or change the dose without your doctor’s advice.

Some studies show that modafinil can reduce EDS, even in patients who have been treat for obstructive sleep apnea with nasal continuous positive airway pressure (CPAP). If you have a diagnosis of obstructive sleep apnea and have excessive daytime sleepiness, talk to your doctor about using modafinil.


Modafinil, a wake-promoting central nervous system (CNS) medicine, is use to treat narcolepsy and obstructive sleep apnea. It’s also use to treat shift work disorder (a condition that causes extreme tiredness or sleepiness during your regular work schedule).

You should not take modafinil if you have a history of liver problems, liver failure, or hepatitis. It may make these conditions worse. You should also avoid drinking alcohol while taking this medicine.

The risk of overdose with modafinil is very low. However, it is important to know how much you have taken before driving a car or doing other dangerous activities.

Tell your doctor if you are taking other medicines, including those to treat depression or anxiety. These medicines can cause more sleepiness or drowsiness when you take modafinil.

Modafinil can increase the chance of getting pregnant if you are using hormonal birth control methods such as pills, patches, vaginal rings, or intrauterine devices (IUDs). If you use these birth control methods while you are taking modafinil, you should use another form of birth control for one month after you stop taking the medicine.


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